Alkaline Clinical Studies

Clinical Improvements Obtained From: The Intake Of Reduced Water Extracts from the Presentation At The Eight Annual International Symposium On man And His Environment in Health And Disease on February 24th 1990, at The Grand Kempinski Hotel, Dallas, Texas, USA by Dr. H. Hayashi, M.D. and Dr. M Kawamura, M.D.

THE CONCEPT OF PREHEPATIC MEDICINES
Since the introduction of alkaline ionic water in our clinic in 1985, we have had the following interesting clinical experiences in the use of this type of water. By the use of alkaline ionic water for drinking and the preparation of meals for our in-patients, we have noticed:

Declines in blood sugar levels in diabetic patients.
Improvements in peripheral circulation in diabetic gangrene.
Declines in uric acid levels in patients with gout.
Improvements in liver function exams in hepatic disorders.
Improvements in gastroduodenal ulcer and prevention of their recurrences.
Improvements in hypertension and hypotension.
Improvements in allergic disorders such as asthma, urticaria, rhinitis and atopic dermatitis.
Improvements in persistent diarrhea which occurred after gastrectomy.
Quicker improvements in post operative bower paralysis.
Improvements in serum bilirubin levels in new born babies.

Being confirming clinical improvements, we have always observed changes of stools of the patients, with the color of their feces changing from black-brown color to a brighter yellow-brown one, and the odor of their feces becoming almost negligible. The number of patients complaining of constipation also decreased markedly. The change of stool findings strongly suggests that alkaline ionic water intake can decrease the production of putrefied or pathogenic metabolites. Devices to produce reduced water were introduced into our clinic in May 1985. Based on the clinical experiences obtained in the past 15 years, it can be said that introduction of electrolyzed-reduced water for drinking and cooking purpose for in-patients should be the very prerequisite in our daily medical practices. Any dietary recipe cannot be a scientific one if property of water is not taken by the patients is not taken into consideration. The Ministry of Health and Welfare in Japan announced in 1965 that the intake of reduced water is effective for restoration of intestinal flora metabolism.

Prevention of Disease with Reduced Water (Alkaline, Ionized Water)
Dr. Sanetaka Shirahata
Graduate school of Genetic Resources Technology Kyushu University Hakozaki Higashi-ku Fukuoka, Japan
"It has long been established that reactive oxygen species (ROS) cause many types of damage to biomolecules and cellular structures, that, in turn result in the development of a variety of pathologic states such as diabetes, cancer and aging. Reduced water is defined as alkaline ionized anti-oxidative water produced by reduction of water. Electrolyzed reduced water (ERW) has been demonstrated to be hydrogen-rich water and can scavenge ROS in vitro (Shirahata et al., 1997).

The reduction of proton in water to active hydrogen (atomic hydrogen, hydrogen radical) that can scavenge ROS is very easily caused by a weak current, compared to oxidation of hydroxyl ion to oxygen molecule. Activation of water by magnetic field, collision, minerals etc. will also produce reduced water containing active hydrogen and/or hydrogen molecule.

Several natural waters such as Hita Tenryosui water drawn from deep underground in Hita city in Japan, Nordenau water in Germany and Tlacote water in Mexico are known to alleviate various diseases. We have developed a sensitive method by which we can detect active hydrogen existing in reduced water, and have demonstrated that not only ERW but also natural reduced waters described above contain active hydrogen and scavenge ROS in cultured cells. ROS is known to cause reduction of glucose uptake by inhibiting the insulin-signaling pathway in cultured cells. Reduced water scavenged intracellular ROS and stimulated glucose uptake in the presence or absence of insulin in both rat L6 skeletal muscle cells and mouse 3T3/L1 adipocytes. This insulin-like activity of reduced water was inhibited by wortmannin that is specific inhibitor of PI-3 kinase, a key molecule in insulin signaling pathways. Reduced water protected insulin-responsive cells from sugar toxicity and improved the damaged sugar tolerance of type 2 diabetes model mice, suggesting that reduced water may improve insulin-independent diabetes mellitus.

Cancer cells are generally exposed to high oxidative stress. Reduced water cause impaired tumor phenotypes of human cancer cells, such as reduced growth rate, morphological changes, reduced colony formation ability in soft agar, passage number-dependent telomere shortening, reduced binding abilities of telomere binding proteins and suppressed metastasis.

Reduced water suppressed the growth of cancer cells transplanted into mice, demonstrating their anti-cancer effects in vivo. Reduced water will be applicable to not only medicine but also food industries, agriculture, and manufacturing industries."

Shirahata, S. et al.: Electrolyzed reduced water scavenges active oxygen species and protects DNA from oxidative damage. Biochem. Biophys. Res. Commun., 234, 269-274, 1997.
Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice. Kim MJ, Kim HK Department of Obesity management, Graduate School of Obesity Science, Dongduk Women's University, 23-1 Wolkgukdong, Seoul, 136-714, South Korea.mijakim@dongduk.ac.kr

Oxidative stress is produced under diabetic conditions and is likely involved in progression of pancreatic beta-cell dysfunction found in diabetes. Both an increase in reactive oxygen free radical species (ROS) and a decrease in the antioxidant defense mechanism lead to the increase in oxidative stress in diabetes.

Electrolyzed reduced water (ERW) with ROS scavenging ability may have a potential effect on diabetic animals, a model for high oxidative stress.

Therefore, the present study examined the possible anti-diabetic effect of ERW in two different diabetic animal models. The genetically diabetic mouse strain C57BL/6J-db/db (db/db) and streptozotocin (STZ)-induced diabetic mouse were used as insulin deficient type 1 and insulin resistant type 2 animal model, respectively. ERW, provided as a drinking water, significantly reduced the blood glucose concentration and improved glucose tolerance in both animal models. However, ERW fail to affect blood insulin levels in STZ-diabetic mice whereas blood insulin level was markedly increased in genetically diabetic db/db mice. This improved blood glucose control could result from enhanced insulin sensitivity, as well as increased insulin release.


The present data suggest that ERW may function as an orally effective anti-diabetic agent and merit further studies on its precise mechanism.


PMID: 16945392 [PubMed - indexed for MEDLINE]Life Sci. 2006 Nov 10;79(24):2288-92. Epub 2006 Aug 2

Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reducing water. Med Hypotheses. 2005;64(3):543-6. Vorobjeva NV. Department of Physiology of Microorganisms, Biology Faculty, Lomonosov Moscow State University, 119992 Moscow, Russia. nvvorobjeva@mail.ru

96-99% of the "friendly" or residential microflora of intestinal tract of humans consists of strict anaerobes and only 1-4% of aerobes. Many diseases of the intestine are due to a disturbance in the balance of the microorganisms inhabiting the gut.

The treatment of such diseases involves the restoration of the quantity and/or balance of residential microflora in the intestinal tract. It is known that aerobes and anaerobes grow at different oxidation-reduction potentials (ORP). The former require positive E(h) values up to +400 mV. Anaerobes do not grow unless the E(h) value is negative between -300 and -400 mV. In this work, it is suggested that prerequisite for the recovery and maintenance of obligatory anaerobic microflora in the intestinal tract is a negative ORP value of the intestinal milieu. Electrolyzed reducing water with E(h) values between 0 and -300 mV produced in electrolysis devices possesses this property.

Drinking such water favors the growth of residential microflora in the gut. A sufficient array of data confirms this idea. However, most researchers explain the mechanism of its action by an antioxidant properties destined to detox the oxidants in the gut and other host tissues. Evidence is presented in favor of the hypothesis that the primary target for electrolyzed reducing water is the residential microflora in the gut.
PMID: 15617863 [PubMed - indexed for MEDLINE]

Testimonials
Bolts gift of health saves dying man.
- July 17, 2009 -

Lying in the hospital bed, my hands shook uncontrollably revealing palms that were white and cold. Should I need help, I could only whisper, an exercise which made me exhausted. A picture of death, I wondered if at 63, I, Joseph James would ever survive to fulfill my dream of attending my daughter’s graduation, my last child.

I began experiencing complications with my colostomy surgery in early March 2009. The bag had been applied following a bout with colon cancer in 2004. On March 25 this year, I was hospitalized and scheduled for abdominal surgery the following day, hopefully my last, as the bag would be removed. However my hopes were dashed. Following surgery the doctor informed me that my bowels were severely damaged by the radiation in 2004. There were major adhesions and the intestines were “paper thin” and powdery, as a result the surgery could not be performed, so they had to close the incision instead. The colostomy continued to malfunction and the doctor said another surgery was necessary, as it appeared there was a blockage. So, on April 5, I was subjected to another surgery at the risk of fistulas forming in the abdominal wall. I had to be fed intravenously and eventually I was given a blood transfusion. The complications began to unravel, the new colostomy worked occasionally. Two fistulas had formed, my blood pressure went up and the medication prescribed to correct the problem increased my heart rate. The fistulas began to leak leading to an infection and the inevitable high fever. The chance of my system becoming septic increased significantly. My family flew in from overseas to say goodbye.

In an effort to identify the cause of the infection, my doctor ran the gamut of tests, but these were futile. As I grew weaker and weaker, the doctors worked tirelessly to keep me alive. A third surgery was imminent, but the doctors decided against this, choosing to use nutrition to allow the body to heal. My family was asked to prepare nutritious liquid meals and feed me daily.

On May 2, I took almost thirty minutes to swallow three tablespoons of pureed food. I felt as though I were deep in the valley of the shadow of death, and my family was in agony, as they watched helplessly. According to my doctor, “only a small number of persons recover from my condition”. Would I become another statistic?

Determined to do everything possible to prevent this, on May 4, and six weeks after being hospitalized, my oldest daughter contacted my very good friend, Naturopath, Dr. Ted Emanuel. I had visited Emanuel in the past, but had transgressed. Ted visited me in the hospital and offered to lend me some natural health products, which he guaranteed would improve my condition. He said he had the products for more than nine months as they were intended to be given to Usain Bolt, courtesy of the Diamond Tree Corporation, in California. However, after numerous attempts to deliver them, in a twist of fate, he offered to let me use them instead. A dying man catching at straws, I willingly accepted. Ted loaned me a few bottles of Ten, a Gratitude bottle, a few sachets of Fermena and a bottle of Fermena Plus; the last one being the flagship product of the company. Engineered by the macrobiotic master and Nobel Prize nominee, Michio Kushi, the products were incorporated into the “Ted Emanuel 331 Dietary Waste Loss Program” and immediately the new nutrition became my daily diet.

The rest, as they say, is history. The fistulas continued to leak, but within four days I started to feel better, and by May 13, there was hardly any sign of a leak. The drips were discontinued and I began walking, sometimes three times daily, as exercise was a critical component of the regimen. The urinal pot and pampers were a thing of the past, and I was now consuming almost eight ounces of pureed food during each meal. The products had such a dramatic effect, that on May 15, nine days after using them, my daughter told the doctors that it was time for me to go home. I was discharged from the hospital, undoubtedly, the doctors were amazed. A post-discharge check-up on May 18, revealed that the fistulas were completely healed and the colostomy bag was working well.

On the day of the graduation my wish came through as I was able to sit through the four- hour ceremony, a proud father, cheering my last daughter as she graduated from high school. I know I have a long way to go, but I am bursting with energy, and grateful to God for giving me another chance. I can now see the blood in the palms of my hands, which were pale before. My friends are so amazed at my recovery. While visiting me in the hospital they had good wishes but very little hope. Emanuel has recommended that I incorporate another Diamond Tree product, Fucoidan (seaweed derivate), which I will be taking along with the other products. I am very happy and thankful for the experience and feel extremely blessed to have a friend as Ted Emanuel, who was totally unselfish in introducing me to these phenomenal Diamond Tree products. I am also fortunate for the twist of fate which made it possible for me to receive the products which were intended for Usain Bolt. Now I am looking forward to being cancer free.

Sincerely Yours,
Joseph James, Auto Engineer
(# 856-7538)

DIAMOND TREE, THE COMPANY
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FERMENA
"I have experienced much more clarity of thought and my mental attitude and emotional well-being has improved significantly. I currently cannot image life without Fermena. It has become an integral part of my diet. "– Sarah V.

FERMENA/FERMENA PLUS
"I can’t deny that these products (Fermena & Fermena Plus) really help in the digestion/elimination process. This has been a BIG issue all my life, and I do see that Fermena and Fermena Plus is making a huge difference."– Clemencia M.

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GRATITUDE
"We all know the intake of water is essential to our good health. When tasting other bottle waters, you can actually taste the difference. Other waters have a taste that is very unlike our clean, refreshing Gratitude water. Plus we all know the importance of minerals and extra hydrating elements our water possesses."– Carl Y.

TEN
"In using the TEN water, I noticed a better recovery time from workouts, a lot better energy. It seems to solve the problems with day-to-day dehydration, day-to-day lack of proper amount of minerals and trace elements, which really were the reasons that my body wasn’t functioning properly."- Jim B.

PASSION TONIC
"I am just passionate about Passion Tonic! I enjoy Passion Tonic in the morning since it is very refreshing, gives me energy and I feel balanced (must be the antioxidants). I love the taste. I keep the bottle at work, so when I feel I need a boost, it’s always available. The Tonic is better for you than all of those caffeine-laden energy drinks."– John T.

"My mom is in her 80’s. She was feeling very fatigued for a while and she’s a very high-energy lady. I gave her the Passion Tonic. Within a week, she was asking “Where’s that miracle juice? That stuff is great.” Her energy returned and she was moving at her normal fast pace. It made a huge difference in her."– Polly M.

ARAZYME
"I’m allergic to all kinds of cosmetics. There are very few things that I can actually use on my face. I have been able to use Arazyme with no allergic reaction. My skin feels great. I think it’s even firmed up my face."- Polly M.

"The Enzina Skin care products are wonderful. The Arazyme safely removes dead skin cells and leaves you with glowing skin after the first use. I also find that my skin moisture level is balanced for the first time in years and I now rarely have the need to use night creams. I love this product and so do my daughters! It's also great for safely addressing teenage acne!!!" – Kathryn H.

BIOSERUM
"I end my day with my husband, Phil, giving me a foot scrub and massage with Bioserum. We have been married for 26 years and he has always rubbed my feet every evening. Now, he has the perfect product to get rid of the rough skin that I have from running and being on my feet. It is wonderful."– Susan S.